2025
Layer-sepcific anatomical and physiological features of the retina’s neurovascular unit.
Current Biology
Grimes WN, Berson DM, Sabnis A, Hoon M, Sinha R, Tian H, Diamond JS. 2025. 2025 Jan 6;35(1):109-120. (link)
2024
Regional tuning of photoreceptor adaptation in the primate retina.
Nature Communications
Saha A*, Bucci T, Baudin J, Sinha R. 2024 Oct 12;15(1):8821. (link)
Predicting manipulating photoreceptor light responses to reveal their role in downstream visual responses.
eLife
Chen Q, Ingram NT, Baudin J, Angueyra JM, Sinha R, Rieke F. Nov 5;13:RP93795. (link)
2023
Regional variation in the organization and connectivity of the first synapse in the primate night vision pathway.
iScience
Saha A*, Zuniga J*, Mian K*, Zhai H, Derr PJ, Hoon M, Sinha R. 2023 Oct 2;26(11):108113. (*equal contribution) (link)
Sensory deprivation arrests cellular and synaptic development of the night vision circuitry in the primate retina.
Current Biology
Wisner SR*, Saha A*, Grimes WN, Mizerska K, Kolarik HJ, Wallin J, Diamond JS, Sinha R, Hoon M. 2023 Oct 23;33(20):4415-4429.e3. (*equal contribution) (link)
2022
Cone photoreceptors in human stem cell-derived retinal organoids demonstrate intrinsic light responses that mimic those of primate fovea.
Cell Stem Cell
Saha A, Capowski E, Zepeda M A F, Nelson E C, Gamm D G, Sinha R. 2022 Mar 03;29(3): 460-471. (link)
Research highlighted in Previews by Angueyra and Li “Video, ergo sum: The search for response to natural light”
Cell Stem Cell
2022 Mar 03;29(3): 349-350. (link)
2021
Research highlighted in UW Madison press release. 2021 (link)
Transient expression of a GABA receptor subunit during early development is critical for inhibitory synapse maturation and function.
Current Biology
Sinha R, Grimes W, Ebbinghaus B, Luu K, Cherry T, Rieke F, Rudolph W, Wong, R, Hoon M, 2021 Aug 19: S0960-9822(21)01049-6. (link)
GABAA presynaptic inhibition regulates the gain and kinetics of retinal output neurons.
eLife
Nagy J, Ebbinghaus B, Hoon M, Sinha R. 2021;10:e60994 DOI: 10.7554/eLife.60994. (link)
Organization and Emergence of a mixed GABA-Glycine retinal circuit that provides inhibition to mouse ON-sustained alpha retinal ganglion cells.
Cell Reports
Sawant A, Ebbinghaus BN, Bleckert A, Gamlin C, Yu WQ, Berson D, Rudolph U, Sinha R, Hoon M. Organization and Emergence of a mixed GABA-Glycine retinal circuit that provides inhibition to mouse ON-sustained alpha retinal ganglion cells, 2021 Mar 16;34(11):108858. (link)
2020
LRRTM4: A novel regulator of presynaptic inhibition and ribbon synapse arrangements of retinal bipolar cells.
Neuron
Sinha R, Siddiqui TJ, Padmanabhan N, Wallin J, Zhang C, Karimi B, Rieke F, Craig AM, Wong RO, Hoon M. 2020 Mar 18; 105(6):1007-1017. (link)
Research highlighted in Previews by Peng and Sampath “LRR-ning the rules: Synapse organization in the primary rod pathway”
Neuron
2020 Mar 18;105(6):949-951. (link)
Shining light on the mode and mechanism of vesicular release at rod photoreceptor synapse.
Biophys J.
Sinha R. 2020 Feb 25;118(4):785-787. (link)
2019
S cone photoreceptors in the primate retina are functionally distinct from L and M cones.
eLife
Baudin J, Angueyra J, Sinha R*, Rieke F. 2019; 8:e39166. (* corresponding author). (link)
2017
Cellular and Circuit Mechanisms Shaping the Perceptual Properties of the Primate Fovea.
eCell
Sinha R*, Hoon M*, Baudin J, Okawa H, Wong RO, Rieke F*. 2017 Jan 26; 168(3):413-426. (*corresponding author). (link)
Research highlighted in Commentary by R.H. Masland “Vision: Two Speeds in the Retina”
Current Biology
2017 Apr 24;27(8):303-305. (link)
2016
Lack of CaBP1/caldendrin or CaBP2 leads to altered ganglion cell responses.
eNeuro
Sinha R, Lee A, Rieke F, Haeseleer F. Oct 2016, 2016 Oct 28;3(5). (link)
2015
Neurotransmission plays contrasting roles in the maturation of inhibitory synapses on axons and dendrites of retinal bipolar cells.
PNAS
Hoon M, Sinha R, Okawa H, Suzuki SC, Hirano AA, Brecha N, Rieke F, Wong RO. 2015 Oct 13; 112(41): 12840-5. (link)
2011
Two synaptobrevin molecules are sufficient for vesicle fusion in central nervous system synapses.
PNAS
Sinha R, Ahmed S, Jahn R, Klingauf J. 2011 Aug 23;108(34):14318-23. (link)
A readily retrievable pool of synaptic vesicles.
Nature Neuroscience
Hua Y*, Sinha R*, Thiel CS*, Schmidt R, Hüve J, Martens H, Hell SW, Egner A, Klingauf J. 2011 Jun 12;14(7):833-9. (*equal contribution). (link)
2010
A common origin of synaptic vesicles undergoing evoked and spontaneous fusion.
Nature Neuroscience
Hua Y*, Sinha R*, Martineau M, Kahms M, Klingauf J. 13, 1451–1453 (2010). (*equal contribution). (link)
2007
Expression pattern of Drosophila translin and behavioral analyses of the mutant.
Eur J Cell Biol.
Suseendranathan K, Sengupta K, Rikhy R, D’Souza JS, Kokkanti M, Kulkarni MG, Kamdar R, Changede R, Sinha R, Subramanian L, Singh K, Rodrigues V, Rao BJ. 2007 Mar; 86(3):173-86.
Book Chapter:
Using fluorescent markers to estimate synaptic connectivity in situ.
Methods Mol Biol.
Hoon M, Sinha R, Okawa H. Using fluorescent markers to estimate synaptic connectivity in situ. Methods Mol Biol 1538 (2017), Humana Press ISBN 978-1-4939-6688-2.